Verizon Wireless Arena, Manchester, NH
Soundcheck: Nothing, Let Me Lie, Friday, Walls of the Cave (Unconfirmed)
Set 1: After Midnight, SlothThe Sloth, AlumniAlumni Blues > LTJPLetter to Jimmy Page > AlumniAlumni Blues, Mellow Mood, Access Me, Llama, All of These Dreams, Curtain WithThe Curtain With > SOAMuleScent of a Mule, ASIHTOSA Song I Heard the Ocean Sing, It's Ice > WotCWalls of the Cave
Set 2: Possum > Light > Mike'sMike's Song > Simple > MakisupaMakisupa Policeman -> Night Nurse -> MakisupaMakisupa Policeman > WedgeThe Wedge, Ghost -> MangoThe Mango Song > WeekapaugWeekapaug Groove -> Llama Reprise
Encore: Show of Life
 "From Goddard College" added to lyrics.
 Magilla tease from Page.
 "Woke up this morning with a policeman at my door all I could do was shrug, and go back in my bedroom and smoke another nug" lyrics.
 Phish debut.
 Heavy Weekapaug teases from Trey.
 Can't You Hear Me Knocking jam with Ghost and Night Nurse lyrics. Unfinished.
Notes: After Midnight was played for the first time since December 31, 1999 (206 shows). In Alumni, Trey added "from Goddard College" after the final "'cause I got a degree" lyric. Simple contained a Magilla tease from Page. Makisupa included the lyrics "Woke up this morning with a policeman at my door all I could do was shrug, and go back in my bedroom and smoke another nug." This show featured the Phish debut of Night Nurse; original artist Gregory Isaacs passed away the night before, October 25, 2010. Weekapaug was heavily teased by Trey in Mango before the segue into Weekapaug itself. Weekapaug subsequently contained a Can't You Hear Me Knocking jam, which featured lyrics from Ghost and Night Nurse, and was unfinished.
This show was part of the "2010 Fall Tour."